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Welcome to the CM Complex™ Page
A KALA Health product


60 Softgel Capsules
Item #1900600

 
To order, click here:

# of Bottles Price Per Bottle
1 $18.95/bottle
2-5 $16.95/bottle
6-11 $15.95/bottle
12 $14.95/bottle
WHAT IS CM COMPLEX?
 

CM Complex™ ("Myristin") contains a combination of long-chain fatty acids extracted from beef tallow, as cetyl esters. The most important ingredient is cetyl myristoleate, but also other cetyl esters of fatty acids are present, all natural substances. Long chain fatty acids are considered different from and superior to ordinary omega fatty acids. 

Myristin® is the name of the original, patented Cetyl Myristoleate (also known as CM or CMO), which was discovered by Harry W. Diehl. Diehl took a fatty acid, myristoleic acid, and combined it with a fatty alcohol molecule, cetyl alcohol, creating cetyl myristoleate. He discovered that it was the presence of this compound in Swiss albino mice that prevented them from developing arthritis. Diehl's laboratory experiments on CM were published in the Journal of Pharmaceutical Sciences in March, 1994.

CM Complex™ softgels are the only softgels on the market containing 40% cetyl myristoleate. The large amount of CMO per softgel (260 mg) allows consumers to take fewer capsules daily and to consume the recommended amount of product in a shorter time.

As a dietary supplement CM Complex™ is used for a little over two months in most cases in a therapeutic dosage of two (people weighing less than approx. 150 lbs) to three capsules daily (adults average to heavy adults). This dosage meets the generally recommended therapeutic dosage of 500 - 600 mg cetyl myristoleate daily.

One CM Complex™ softgel is best taken three times daily with water on an empty stomach, about 30-45 minutes before meals, or three softgels should be taken in the morning, if that fits your daily schedule better. 

For Patient Studies with Long Chain Fatty Acids : CLICK HERE

CM Complex™ offers the following benefits:
 

•  

CM Complex™ is stabilized through a proprietary process that prevents oxidation and toxicity. The stable fatty acids bring quick relief from the discomforts of a variety of auto-immune diseases.

•  

CM Complex™ softgels ("Myristin®") are the only 40% CMO softgels on the market. The large amount of CMO per softgel (260 mg) allows consumers to take fewer capsules daily and to consume the recommended amount of product in a shorter time.

WHAT DOES CM COMPLEX™ DO?

The long-chain fatty acids in CM Complex work in similar fashion as omega Essential Fatty Acids (EFAs). Essential fatty acids benefit the arachidonic acid metabolism which in turn results in the formation of beneficial prostaglandins and limits the production of bad prostaglandins. 

ADVANTAGES OF CM Complex™

  • CM Complex™ is a powerful nutritious supplement which aids the body’s own healing system and returns cells to a state of balance;
  • CM Complex™ contains molecules with anti-inflammatory properties;
  • CM Complex™enhances the transfer of nutrients through cell membranes;
  • CM Complex aids joint movement (flexibility).

KALA HEALTH CM Complex™ is
available in bottles containing
60 Softgels

Supplement Facts

Serving Size: 2 Softgels
Servings Per Container: 30
  Amount Per 2 Softgels

 % Daily Value

Cetyl Myristoleate (long chain fatty acid cetyl ester) 520 mg

*   Daily value not established

Other Ingredients:
Gelatin, Glycerin, Purified water, Caramel, Titanium dioxide

Recommended Use:
For adults, as a dietary supplement, take one softgel capsule two to three times daily or as directed by your health care provider. Contains no yeast, sugar, starch, artificial flavor, color or added preservatives. Store in cool, dry place.

 

THE SCIENCE BEHIND 
CM COMPLEX™

    CM Complex™ ("Myristin" brand) is a concentrated long-chain fatty acid complex. An explanation of how long-chain fatty acids work is therefore meaningful.
    It is unknown exactly how CM works, but it is worth exploring the many possibilities that have been proposed based on clinical observations of symptom improvement, scientific reviews of the chemistry of CM and published data on one of the fatty acids in the complex. 
    A review of the recent literature on fatty acids shows standard polyunsaturated fatty acids (PUFAs) are effective agents for inflammation relief.1-4 Fish oils rich in n-3 fatty acids have demonstrated anti-inflammatory effects against arthritis in numerous studies.5-7     
    Most studies attributed modulation of immune and inflammatory response to eicosanoids and cytokine- mediated effects.8 Cytokines and certain eicosanoids are implicated in inflammatory conditions. It is thought that CM may work through a similar but as yet unknown mechanism, although there is some evidence that n-5 and n-9 fatty acids form oxygenated metabolites through transcellular processing and that these exert anti-inflammatory effects distinct from eicosanoids.9
    A striking difference between the effect of CM and PUFAs is the longer-lasting effects CM appears to have. It is thought this may be due to some type of "reprogramming" of T cells. This brings us to another proposed mechanism of action, N-myristoylation.
    Cytokine activity is linked to N-myristoylation, a process in which myristic acid is bound to the glycine residues in specific membrane proteins and is responsible for their activation. There is some evidence that human myristoylation may occur with other 14-carbon fatty acids, and perhaps include myristoleic acid.10 And, in fact, a recent study identified myristoleic acid as the cytotoxic component in saw palmetto (Serenoa repens) that induces apoptosis in human prostate cancer cells.11 These receptors bind cytokines with high affinity, which in turn initiates intracellular signals that alter the behavior of the effector cell.12
Cellular behaviors that can be affected include various secretions, gene transcription, chemotaxis, and proliferation and differentiation of hematopoietic stem cells, including T cells. These behaviors directly affect immune function and inflammatory activities and some affect pain response.13 

References: CLICK HERE

 



60 Softgel Capsules
Item #1900600

# of Bottles Price Per Bottle
1 $18.95/bottle
2-5 $16.95/bottle
6-11 $15.95/bottle
12 $14.95/bottle

No questions asked,
cetyl myristoleate CMO - like anti inflammatory nutraceutical
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cetyl myristoleate CMO - like anti inflammatory nutraceutical


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KALA Health, Inc.
108 Woods Hole Road, Falmouth, MA 02540
Mailing Address: P.O. Box 936, Falmouth, MA 02541

ORDER: (800) 998-8813
PHONE: (508) 495-4034
FAX: (508) 495-4035

This site was last updated on December 26, 2007

DISCLAIMER
The information contained in this site has been compiled from numerous studies, research papers and journals for the purpose of offering consumers and professionals information about our health and nutrition products. None of the information herein should be construed as a claim for cure, treatment or prevention of any disease. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. All matters regarding physical health should be referred to your own health care provider or other medical professional. The statements in this web site regarding dietary supplements have not been evaluated by the Food and Drug Administration. All rights reserved. No part of this web site may be reproduced in any manner for the public or private use without the written permission of KALA Health, Inc., except in the case of quotes embodied in critical articles or reviews. Entire site copyright 2004-2007.